Excess Iron – The Iron Overload Resource for International HCPs

Signs of iron overload (also known as excess iron) may be seen after as few as 10 red blood cell transfusions, making iron overload a common secondary disease among transfusion-dependent patients. Patients with chronic severe anemias caused by thalassaemia, sickle cell disease, and myelodysplastic syndromes requiring blood transfusions are at greatest risk.

The most common cause of iron overload is hereditary haemochromatosis, a condition linked to a mutation of the HFE gene. Among untreated homozygous patients, the disorder typically leads to significant iron overload by the 4th or 5th decade of life.

Excessiron.com, your excess iron resource, helps keep you informed with the latest news on
haematology and iron overload.

The Global Iron Summit was held November 2-3, 2007 in Frankfurt, Germany, Click here to view the Summit agenda, faculty presentations and bios.

Clinical effects of biapenem on febrile neutropenia in patients with hematological malignancy
Inherited and acquired variations in the hyaluronan synthase 1 (HAS1) gene may contribute to disease progression in multiple myeloma and Waldenstrom's macroglobulinemia
Treatment of refractory acute GVHD with third-party MSC expanded in platelet lysate-containing medium

Sibling history of asthma is a risk factor for pain in children with sickle cell anemia
Hematopoietic stem cell transplantation in thalassemia